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Finding of staphylococcus aureus at adult age

Question
Hello,
I (female, 28 years old, chronic colonization with Pseudomonas aeruginosa since early childhood) have had for the first time the finding of Staphylococcus aures in the last sputum. Apart from penecillin, there are seemingly no resistances.
My health condition is actually quite good, I was able improve my FEV1 from 24% in the year 2011 to 34% FEV1 and with this also reduce my need of additional oxygen via a strong therapeutic regimen (azithromycin orally and aztreonam + colistin inhalative as permanent antibiotic therapy, every 6-8 weeks i.v. with changing antibiotics). My physical capacity is as good as it has not been for years.
Should one now react to the new finding or rather wait and see?
Many thanks!
Answer
Hello!
The first finding of Staph. aureus is indeed not such an alarming result as the finding of Pseudomonas aeruginosa, should however in spite of this be taken for serious. As your lung function is after all markedly reduced, I would recommend, to treat the Staphylococcus with an effective, oral antibiotic drug (e.g. flucloxacillin or amoxicillin). You should continue to take azithromycin. Probably it is good to know, that aztreonam has also a certain effect on Staph. aureus, therefore it would make sense to take the oral antibiotic in parallel to the aztreonam inhalation.

Best regards,
Dr. Rainald Fischer
29.07.2014