User login
Enter your username and password here in order to log in on the website:
Please note: While some information will still be current in a year, other information may already be out of date in three months time. If you are in any doubt, please feel free to ask.
Vaccination against Pseudomonas?
- Question
- Hello,
is there any research concerning a vaccination against Pseudomonas? Could daily anti-bacterial mouth washings help to avoid a colonization with Pseudomonas?
Many thanks! - Answer
- Dear questioner,
there is indeed a vaccination against Pseudomonas aeruginosa, that is targeted against certain parts of the germ, that play an important role for the colonization. A clinical study has also been conducted on this vaccination, that has been published 2007 in a very good journal: Döring et al. Proc Nat Acad Science. In this study it has been shown, that the vaccine led to fewer infections with Pseudomonas aeruginosa. If this vaccine is however indeed used by the CF centers is questionable, as at the same time, the procedure in case of the first finding of Pseudomonas has changed.
In the meantime one tries to avoid a colonization with this germ via an early eradication therapy with antibiotic drugs. The success of this therapy is also very good.
A good oral hygiene is for sure important. However, that anti-bacterial or better anti-septic oral washings prevent a colonization with the germ, is very improbable. To my knowledge, there are no clinical studies about this. However, there is a study, that investigates the influence of gargeling with specific antibodies on the prevention of a colonization with Pseudomonas (IgY). The study is still ongoing, so that there are no results here, yet.
Best regards,
Barbara Kahl - 12.09.2015
