Hair loss due to liver cirrhosis?

Question

Hello,
Our 18-year-old son has CF-related liver cirrhosis; his liver function tests, vitamin levels, etc., are checked every three months. He takes Kaftrio and Kalydeco. For the past few weeks, he has occasionally mentioned experiencing increased hair loss. I have read that this can indeed occur with liver cirrhosis—though I haven't been able to determine whether such a deficiency symptom can still arise even when supplementation is regularly monitored. The supplement he takes contains the following vitamins and minerals: vitamins A, D3, E, K1, C, B1, B2, niacin, B6, biotin, pantothenic acid, zinc, selenium, and coenzyme Q10. Our son eats a varied and healthy diet, exercises regularly, and is extremely attentive to his health.
What is your assessment of this hair loss issue, and are there ways to counteract it? Generally speaking, this is a relatively minor problem, but I fear an 18-year-old might not see it that way.
Thank you very much for your reply!

Answer

Dear inquirer,

You have reported the recent onset of hair loss in your 18-year-old son, who suffers from cystic fibrosis and liver cirrhosis. You mention that he is already receiving supplements for vitamins, minerals, and trace elements. You are asking what measures can stop the hair loss and how a recurrence can be prevented.

In principle, it is true that liver cirrhosis can contribute to hair loss. The causes are usually multifactorial, including hormonal changes, nutritional deficiencies, metabolic disorders, and impaired liver detoxification function.

Therefore, the primary focus is on treating the underlying condition. The goal is to maintain the most stable liver function possible and to consistently avoid nutritional deficiencies. It is also important to strictly avoid substances that damage the liver—especially alcohol—and, in consultation with the treating physicians, to avoid non-essential medications that place a strain on the liver.

Regular check-ups at the specialized CF clinic and with a hepatologist are crucial for optimizing therapy and preventing the progression of liver cirrhosis.
Body weight should also be monitored, as weight gain is possible during modulator therapy.
Furthermore, targeted monitoring and—if necessary—supplementation of the following nutrients are essential: zinc and selenium, fat-soluble vitamins (A, D, E, K), B vitamins, and iron.
Regular blood tests and ongoing nutritional counseling are recommended for this purpose.

Regardless of the liver disease, other potential causes of hair loss should also be considered. These include, for example, stress, thyroid disorders, or hormonal changes. An appropriate medical evaluation by an internist is therefore advisable. We hope this information proves helpful and supports you in your upcoming discussions with your treating physicians.


Kind regards,
Dr. Christina Smaczny

29.06.2026