Topics

DNA
How many DNA variants are examined when CF is suspected?
23.03.2010
Lung problems in CF
What causes cystic fibrosis lung disease?
23.03.2010
Numbers of patients with CF
I read in a CF leaflet information on number of patients. 1.300 in the Netherlands, 23.000 in Europe and 25.000 in the US. The numbers are surprising and not related to the population in the different continents. What is the explanation: social standards, healthcare in the specific countries or parts of the world. Or is there an issue of registration?
23.03.2010
Late diagnosis
I would like to pose the following question. Our 16 year old son has had sinusitis for years, for which he was operated on twice by an ENT surgeon. He’s also known with bronchitis. Additionally he has regularly tummy-aches and diarrhea. All together, he doesn’t have worrying symptoms, he does daily sport and has a normal development. Because of the persisting ENT problems, the ENT surgeon consulted a pediatrician and a sweat test was done twice, both times with low positive chloride (57?). Additionally blood was taken for DNA and I now worry. Is there a chance that a child with normal development and already 16 years old of age would have CF only now. Thanks for your answer.
23.03.2010
Genetics
How can you explain that only one in four children has CF and not all children?
23.03.2010
salty sweat
Why is the sweat more salty in a CF patient?
23.03.2010
recessive CF carrier and pancreatic problems
I am a possibly carrier of the CF-gene, the disease being present in my family. I know that mild forms of the disease may be present in CF-carriers, for example resulting in infertility (a disease also prevalent in my family). My question is the following: “Is it possible, being a carrier, not to have complaints like infertility, but presenting with decreased pancreatic function, resulting for example in loose fatty stools when eating fatrich food. Is there a lab-test to detect these forms? Or does this type of disease not exist? Testing for CF carriership is planned soon. Thanks for your answer. With kind regards
23.03.2010
Birds
Is there a problem for children with CF to have a paroquet as a pet?
23.03.2010
Cystic Fibrosis (CF)
What are the main mechanisms of disease in CF?
23.03.2010
IRT value
Hello! Since our 3 year old son has CF (del-F508 mutation) our newborn baby (35th week of pregnancy) was screened more extensively. As a result we were told that the IRT value is unremarkable. We assumed, thus, that CF can be excluded. But sometime a sweat test is planned to be done. Wouldn’t a genetic test make more sense? Would we have to assume the same mutations? Since our older son already tasted very salty as a baby wouldn’t our baby have to taste as salty as well? Many thanks for answering.
23.03.2010
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