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Reflux
- Question
- How come reflux is such a common thing in people with CF?
- Answer
- Dear ECORN-user,
Gastro-oesophageal reflux is indeed quite common in patients with CF. Some physicians even think it is part of the primary problem in cystic fibrosis. Others think it is due to the lung disease. Indeed lung disease in CF leads to hyperinflated lungs, so that a higher work of breathing needs to be done which leads to a higher negative pressure in the thorax. On top of that patients with cystic fibrosis will cough a lot. Positive pressure in the belly and negative pressure in the thorax makes that there is an ideal gradient for food to flow back from the stomach to the oesophagus with possible aspiration in the lungs.
Kind regards,
Prof. Dr. K. De Boeck
- 05.06.2012
