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Staphylococcus aureus
- Question
- I am 29 years old; I am coumpound heterozygous for deltaF508 and R347P mutations. I was chronically infected by Staphylococcus aureus and took Minocycline since 2006, because of frequent exacerbations and recurrent use of intravenous antibiotic courses. With this treatment I feel very well. Recently, my physician has changed and he stopped my treatment because there wasn't Staphylococcus aureus in my sputum anymore. I am very worried because my previous doctor has recommended to maintain the treatment for all my life!! My question is so: is it a good idea to stop the treatment?
- Answer
- Minocycline is a very usefull antibiotic in CF patients infected by Staphylococcus aureus. It has antibiotic properties but also immunomodulating properties. Since the treatment is now stooped I propose to evaluate your respiratory status in the next months. If your respiratory status remains stable, there is no indication for treatment. At the opposite, if you will support frequent exacerbation it will be useful to start again Minocycline treatment for a long period.
Prof. Isabelle Durieu - 11.06.2012
