Anti-reflux

Question

Hello.
We have a child who has cystic fibrosis and we would like to know if the anti-reflux medications, from a general point of view, were unsuitable for them?
I'm not an expert but it seems to me that these drugs are designed with the aim to "stuff" and therefore they could harm the liquefaction?
Thank you.

Answer

Dear questioner,
Gastroesophageal reflux disease is common in cystic fibrosis, as evidenced by various studies finding an incidence of 25 to 50%, much higher than in the general population.
This reflux has multifactoral origin and may be accompanied by clinical symptoms, but sometimes, it is asymptomatic. It can have a negative impact on lung development and it is important to take reflux into account and to treat it early.
Hygiene and dietary measures, medical (or even surgery) treatment could be discussed. For CF patients, “anti-acids” treatments are not contra-indicated, especially inhibitors of the proton pump (e.g. omeprazole). These treatments which reduce gastric acid secretion are frequently prescribed for CF patients. Some thickeners are likely to change transit and should be used with caution.
Of course, it is important not to initiate treatment without medical advice, and the doctor of your CF centre will propose the most suitable anti-reflux treatment for your child.
Best regards,
Dr Michèle Gérardin

15.07.2013