User login

Enter your username and password here in order to log in on the website:
Login

Forgot your password?

Please note: While some information will still be current in a year, other information may already be out of date in three months time. If you are in any doubt, please feel free to ask.

Lung after DLTX (double-lung transplantation)

Question
Dear expert team,
in case a CF patient has had a lung transplantation, is and stays the lung "free of CF" then? That means: does it not congest with mucus anymore? Or does one have to go on with physiotherapy and inhale mucolytic drugs?
Many thanks!
Answer
Hello,
the genetic defect is not present in the "new" lung, so that practically everything should be fine. However, the germs stay in the "airways of the recipient", that are not replaced (nose-/thorat area, trachea, large bronchi), so that therefrom a new infection of the lung is possible. Furthermore, the new lung is not fully "healthy" due to rejection inspite of immunosuppression and cannot protect itself as well as a healthy lung against bacteria and viruses.
Bets regards,
Prof. Dr. TOF Wagner
17.02.2014