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Organ donor

Question
Can the mother or father of a CF child be a donor if transplant is required or does the fact to be a healthy carrier excludes that possibility ? Thank you
Answer
Dear questioner,

Parents of a CF child are healthy carriers of one mutation in the CFTR gene. They have no organic CF disease and therefore they can give their organs for donation without problems in relation to cystic fibrosis.

If your question implies to make a donation for your child, lung transplantation with a living donor is no longer performed to my knowledge in France. It takes 2 donors who give each one lobe to the child, each lobe constituting one lung for the child. This implies that the child is still small for morphological suitability. This surgery is therefore a risk-taking for 3 people and has a consequence a degree of respiratory failure for the donors. Nevertheless, a kidney transplant is quite possible if needed and if you are immunologically-compatible.

Best Regards
Dr Isabelle Danner-Boucher
30.01.2015