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Pancreatic sufficiency


My 7 month old baby has CF (26AG and G542X mutations), it is currently pancreatic sufficient.
If it lasts over time, from what age on can we expect him to be pancreatic insufficient and it will remain for life?

thank you

CF patients are pancreatic insufficient in the majority of cases (80-85%). However, some mutations are known to be associated more frequently with pancreatic sufficiency. "26AG" is not a complete name: perhaps is it the mutation 3272-26A> G? In this case, more than half of the patients with this mutation are pancreatic sufficient.

The status of pancreatic sufficient may change over time, particularly during the first years of life. The recommendations are therefore to control fecal elastase regularly once a year during this period, then to check in case of gastrointestinal symptoms suggestive of exocrine pancreatic insufficiency (difficult weight gain, abdominal pain, abnormal stools).

Kind regards
Dr Michèle Gérardin