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I am carrying the F508del, I am 21 years old I am diabetic and I have a thyroid dysfunction (hypo) and I take the pill "leeloo®". I saw several articles on the need to focus most heavily dosed ethinylestradiol pills. Concrening CF articles I see the opposite. What is that about? In addition is there a risk of inefficiency of the combined pill when taken with other antibiotics (amoxicillin + clavulanic acid, ciprofloxacin, trimethoprim)? Thank you in advance cordially

the combined oral contraceptive pill is authorized for patients with cystic fibrosis. Although literature suggests links between estrogen and lung exacerbations, the evidence is conflicting and there is currently no argument for using one type of pill or another. In the non-CF-related diabetes patients, estrogen plus progestin contraception is allowed except in very complicated cases or very long lasting diabetes (over 20 years).
So you can continue to use your pill if you tolerate it well.
The interactions may occur with some medications. For antibiotics especially with rifampicin; otherwise interactions with ORKAMBI® are reported.

Best regards,
Pr I. Durieu