User login

Enter your username and password here in order to log in on the website:

Forgot your password?

Please note: While some information will still be current in a year, other information may already be out of date in three months time. If you are in any doubt, please feel free to ask.

Pseudomonas Vaccine

Could you give me some news regarding a vaccine against Pseudomonas. A clinical trial was ongoing and had to end on 2015 (I read this on a posted question)

You refer to this question :

Inclusions in this phase II/III (not specific to CF) ended on july 2015.
Results published on february 2017 show a lack of efficacy of IC43 (vaccine-candidate against Pseudomonas aeruginosa) in ventilated intensive care patients (all pathology).
799 patients were randomized to receive either IC43 or a placebo. The primary endpoint was the mortality rate 28 days after injection.
The percentage of death is 29,2 on the IC43-group and 27,3 in the placebo –group.
Best regards
Anna Ronayette