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Rare mutation

Dear expert team,
my son is 20 years old and suffers from CF with a combination of delF508 and 525 delT.-Mutation. I am interested to which group of mutations the second mutation belongs (exon 4-frameshift) and if my son was a candidate for the new triple combination of VX-445.
Best regards,
Dear questioner,
the clinical trial on the triple therapy with VX-445 lists as a crtierum for taking part in it: "This study will evaluate the efficacy of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are heterozygous for F508del and a minimal function mutation (F/MF subjects)." (Quelle: 525delT (also known as c.393delT or p.Phe131LeufsX3 is a mutaion with frameshift and is therefore unfortunately not a CFTR variant with minimal function. However this is only the criterium for taking part in the study it is not know already if this drug is effective in patients with the combination F508del and a stop-mutation due to a frameshift.
Best regards,
Frauke Stanke