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Tobi® and nebulizer
- Question
- Hello,
which nebulizer is suitable for TOBI® (tobramycin inhalation solution)?
According to the leaflet, the LC-Plus nebulizer should be taken. Is this absolutely necessary or can one also take standard nebulizers respecitvely is the eFlow also suitable? Many thanks for your answer. - Answer
- Dear questioner,
we got the following answer per mail from Kathrin Könecke-Georg:
"The company PARI has published several drug measurements.
Among others, TOBI® 300 has been tested with the eFlow rapid nebulizer concerning its deposition in the lung and the serum concentrations.
For TOBI® 300, the eFlow rapid nebulizer is as suitable as the LC plus nebulizer (original studies, Ramsey et al.). Hereby, there is a clear time-saving effect with the eFlow rapid nebulizer.
The serum concentrations are 60 minutes after the inhalation of TOBI® 300 with the eFlow rapid nebulizer comparable to those of the standard therapy with the LC-Plus nebulizer (Hubert et al, 2007).
In summary: TOBI® can be inhaled mit the standard nebulizer, thus LC-Plus, as well as with the eFlow rapid nebulizer."
Best regards,
Annette Pfalz for ECORN-CF - 26.05.2014
