Inloggen

Voer uw gebruikersnaam en wachtwoord hier in om in te loggen op de website:
Inloggen

Wachtwoord vergeten?

Please note: While some information will still be current in a year, other information may already be out of date in three months time. If you are in any doubt, please feel free to ask.

Inheritance of CF

Vraag
Dear experts,
can you tell me, if a child of parents, both suffering from CF, will be born with CF in any case? Or is there a chance that such a child will be born healthy or as a carrier?

Best regards,
Antwoord
Hello,
in case both parents are suffering from CF, every child they have together will suffer from CF itself.
Background: In case of autosomal-recessive illnesses like CF, patients do have two mutated genes (CFTR), from which one is inherited from the father and one from the mother. Because every human being has only two CFTR-genes, which both show the mutation in case of CF patients, children from two CF-patients can only inherit mutated CFTR-genes and will therefore suffer from CF in any case.
Yours sincerely,
Prof. Dr. M. Stuhrmann-Spangenberg
16.06.2008