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Calprotectin and thickening of the walls of the large bowel
- Question
- Hello,
my calprotectin values in the stool are increased, between 115 and 150, furthermore a thickening of the bowel wall in the colon descendens could be detected in the ultrasound. Now it is discussed in the CF center, if an endoscopy of the bowel would be necessary. Are increased values of calprotectin normal in case of CF? Would you recommend an endoscopy of the bowel? Many thanks for your answer,
Best regards,
- Answer
- Hello,
we received the following answer per mail from PD Dr. Martin Welker, university hospital of Frankfurt, Germany:
"The value of the fecal calprotectin can be increased in case of different inflammations in the bowel - also caused by bacteria. Even if this has not been investigated in large studies, one knows that fecal calprotectin is not increased in all patients with CF; an increased fecal calprotectin is therefore not "normal" in case of CF. One speculates, that increased values of calprotectin can also in case of patients with CF hint at inflammations of the bowel (small bowel, large bowel).
The indication for an endoscopy of the bowel (coloscopy) can not be made solely based on the fecal calprotectin value. This is an individual decision, that has to be communicated with you personally by the treating physician."
Best regards,
Mit freundlichen Grüßen
Annette Pfalz für ECORN-CF
- 18.08.2014
